Table 4. Immunohistochemical scores.
| No. | c-kit | VEGFR-2 | PDGFR-2 | PI3K | Akt | m-TOR | MEK1 | MEK2 | ERK | |
|---|---|---|---|---|---|---|---|---|---|---|
| HSA | 1 | - c) | 3+ | - | 1+ | - | 1+ | - | 2+ | - |
| 2 | - | 2+ | - | 1+ | - | 1+ | 1+ | 2+ | - | |
| 3 | - | 3+ | - | 1+ | - | 1+ | 1+ | 2+ | - | |
| 4 | 1+ | 2+ | 2+ | 1+ | - | 1+ | 1+ | 2+ | 1+ | |
| 5 | - | 1+ | - | 1+ | - | - | - | 1+ | - | |
| 6 | - | 2+ | 2+ | 2+ | - | - | 1+ | 2+ | - | |
| 7 | - | 2+ | - | 1+ | - | 1+ | 1+ | 2+ | - | |
| 8 | 1+ | 2+ | 1+ | 2+ | - | - | - | 3+ | 1+ | |
| 9 | - | 2+ | 1+ | 1+ | - | 1+ | 1+ | 2+ | - | |
| 10 | 1+ | 2+ | - | 2+ | - | 1+ | 1+ | 2+ | - | |
| % a) | 1+ d) | 30 | 10 | 20 | 70 | 0 | 70 | 70 | 10 | 20 |
| 2+ e) | 0 | 70 | 20 | 30 | 0 | 0 | 0 | 80 | 0 | |
| 3+ f) | 0 | 20 | 0 | 0 | 0 | 0 | 0 | 10 | 0 | |
| Total b) | 30 | 100 | 40 | 100 | 0 | 70 | 70 | 100 | 20 | |
| Control | 11 | - | - | - | - | - | - | - | - | - |
| 12 | - | - | - | - | - | - | - | - | - |
a) %, percentage of specimens with each staining score; b) Total, proportion of specimens with any positive score; c) -, <10% of positive cells; d) 1+, 10% to <30% of positive cells; e) 2+, 30% to <50% of positive cells; f) 3+, >50% of positive cells.