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. 2016 Jan 29;78(4):657–668. doi: 10.1292/jvms.15-0387

Table 1. Type of interaction between doxorubicin and deracoxib in CMT-U27 cells.

Combination of DOX with DER RI value
DOX (0.9 µM)
DOX+ DER (50 µM) 2.24 (synergistic)
DOX+ DER (100 µM) 1.98 (synergistic)
DOX+ DER (250 µM) 2.33 (synergistic)
DOX (0.09 µM)
DOX+ DER (50 µM) 1.15 (additive)
DOX+ DER (100 µM) 1.13 (additive)
DOX+ DER (250 µM) 1.08 (additive)

DOX, doxorubicin; DER, deracoxib; RI, ratio index. Type of interaction: RI≥1.5, synergistic; RI<1.5 to >0.5, additive; RI≤0.5, antagonistic interaction.