Table 4.
High resolution esophageal manomtery and Timed barium esophagram findings: Adjusted analysis1
| Outcome | PD | LHM | POEM | P value |
| Eckardt score | 2 | -5.7 (-6.7, -4.5) | -5.6 (-6.1, -5.2) | 0.94 |
| HREM | ||||
| Post-Pre basal mean pressure (mm Hg) | 2 | -27.5 (-30.3, -24.5) | -33.1 (-38.0, -27.6) | 0.084 |
| Post-Pre LES-IRP pressure (mm Hg) | 2 | -20.1 (-22.2, -17.9) | -20.9 (-24.7, -16.5) | 0.76 |
| TBE | ||||
| Post-Pre height at 1 min (cm) | -2.7 (-5.1, -0.05) | -4.6 (-5.5, -3.7) | -5.4 (-7.1, -3.5) | 0.21 |
| Post-Pre width at 1 min (cm) | -1.4 (-1.9, -0.77) | -1.3 (-1.5, -1.03) | -1.7 (-2.2, -1.2) | 0.28 |
| Post-Pre volume at 1 min (cc) | -81.8 (-112.4, -44.3) | -79.3 (-92.7, -64.8) | -95.6 (-119.4, -67.6) | 0.58 |
| Post-Pre height at 5 min (cm) | -5.8 (-7.7, -3.7) | -6.0 (-6.8, -5.2) | -5.8 (-7.3, -4.1) | 0.95 |
| Post-Pre width at 5 min (cm) | -1.6 (-2.4, -0.74) | -1.5 (-1.8, -1.1) | -1.9 (-2.5, -1.3) | 0.47 |
| Post-Pre volume at 5 min (cc) | -68.2 (-89.9, -43.5) | -51.2 (-60.9, -41.0) | -64.6 (-82.0, -45.3) | 0.28 |
1ANOVA analysis was used to obtain adjusted means. A logarithm transformation of each outcome [ln(y -1 + min(y)] was modeled as the outcome variable with age at time of treatment, BMI and having had previous treatments as the independent variables. 2Data not available Only 3 patients in PD group had HREM testing done both pre- and post-treatment, hence this group was not included in the models. Values presented as mean (95%CI). PD: Pneumatic dilation; LHM: Laparoscopic Heller myotomy; POEM: Peroral endoscopic myotomy; HREM: High resolution esophageal manomtery; TBE: Timed barium esophagram; LES: Lower esophageal sphincter; IRP: Integrated relaxation pressure.