Table 5. Preparation of DV230-Ficoll with Varied CpG-ODN Loadings Induced Similar Levels of IL-6 from Human B Cells.
sample | Mal/Ficoll molar ratio | DV30/Ficoll molar ratio | conjugation efficiency (%) | induction of IL6 - EC50 (μM) | induction of IL6 - Geomean max (pg/mL) |
---|---|---|---|---|---|
1 | 28 | 24 | 86 | 0.028 | 745 |
2 | 61 | 53 | 87 | 0.022 | 844 |
3 | 101 | 82 | 81 | 0.017 | 777 |
4 | 185 | 154 | 83 | 0.017 | 984 |