Table 1.

Univariate and multivariate analysis of factors associated with death during antituberculous treatment in the district of Manhiça (2011–2012)

	Total analysed		Outcome of treatment				uOR (95 % CI)	p value	aOR (95 % CI)	p value*
	N#	%	Death N	(%)	Alive N	(%)
Year
2011	946	48.3	157	16.6	789	83.4	Ref	0.063	Ref	0.87
2012	1011	51.7	137	13.6	871	86.4	0.79 (0.62–1.01)		1.03 (0.73–1.44)
Age
< 15	224	11.5	24	10.7	200	89.3	Ref	0.071	Ref	0.093
15–24	174	8.9	25	14.4	149	85.6	1.40 (0.77–2.54)		1.57 (0.49–5.01)
25–34	625	32.1	91	14.6	534	85.4	1.42 (0.88–2.29)		1.40 (0.48–4.01)
35–44	407	20.9	75	18.5	331	81.5	1.89 (1.15–3.09)		1.73 (0.58–5.14)
45–54	258	13.2	34	13.2	223	86.8	1.27 (0.73–2.22)		1.56 (0.51–4.77)
> 55	261	13.4	45	17.3	215	82.7	1.74 (1.03–2.97)		2.45 (0.80–7.50)
Sex
Female	856	43.9	118	13.8	738	86.2	Ref	0.15	Ref	0.041
Male	1096	56.2	176	16.1	917	83.9	1.20 (0.93–1.54)		1.39 (1.01–1.91)
AFB smear at diagnosis
Positive	750	51.7	89	11.9	658	88.1	Ref	0.005	Ref	0.009
Negative	701	48.3	120	17.1	581	82.9	1.52 (1.13–2.05)		1.54 (1.12–2.13)
TB Category
New Case	1746	89.9	260	14.9	1485	85.1	Ref	0.45
Retreatment	195	10.1	33	16.9	162	83.1	1.16 (0.78–1.73)
Type of TB
Pulmonary	1630	83.4	237	14.6	1390	85.4	Ref	0.17	Ref	0.61
Extra-pulmonary	325	16.6	57	17.5	268	82.5	1.25 (0.91–1.71)		0.87 (0.52–1.47)
HIV status
HIV uninfected	540	28.2	45	8.4	494	91.7	Ref	<0.001	Ref	<0.001
HIV infected not on ART	811	42.4	164	20.2	647	79.8	2.78 (1.96–3.95)		3.50 (2.13–5.74)
HIV infected on ART	563	29.4	70	12.5	491	87.5	1.56 (1.05–2.32)		1.83 (1.07–3.14)

uOR unadjusted Odd Ratio, aOR Adjusted Odds Ratio, ARV On antiretroviral treatment, AFB acid fast bacilli

*p-value obtained through likelihood ratio test (LRT)

^#In some variables (age, age, sex, AFB smear, TB category and TB type and HIV status) there is missing data, because these data were not available