Table 1. Properties of ss-InFroMs formed from diverse biologically active cargo.
Compound | Drug:F127 molar ratio | Drug Concentration (mg ml−1) | Size (nm) | PDI* | Log P† | [NaCl](M) |
---|---|---|---|---|---|---|
α-Tocopherol | 17 | 39 | 86 | 0.26 | 8.8 | 2 |
Cabazitaxel | 8 | 41 | 62 | 0.10 | 3.7 | 3.5 |
Coenzyme Q10 | 30 | 43 | 82 | 0.28 | 9.9 | 4 |
Cholecalciferal | 29 | 62 | 45 | 0.16 | 8.0 | 2 |
Cyclosporine A | 15 | 7 | 165 | 0.34 | 4.1 | 3 |
Ergocalciferol | 12 | 25 | 112 | 0.31 | 7.8 | 2 |
Ivermectin | 45 | 80 | 39 | 0.03 | 4.4 | 0 |
Retinal palmitate | 14 | 33 | 114 | 0.25 | 10.1 | 2 |
Squalene | 44 | 80 | 81 | 0.28 | 8.6 | 2 |
Teststorone undecanoate | 10 | 60 | 112 | 0.19 | 6.7 | 4 |
Vitamin K1 | 51 | 150 | 74 | 0.25 | 8.5 | 0 |
Values represent the mean from three independent preparations.
*Polydispersity index.
†Calculated with the ALOGPS 2.1 algorithm.