Table 1.
Microorganism inactivation ability of different sterilization techniques.
Category | Technique | Inactivation level | Mycobacteria | Vegetative bacteria | Bacteria spores | Nonenveloped virus | Enveloped virus | Prions | Fungal |
---|---|---|---|---|---|---|---|---|---|
Heat | Heat treatment | High | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Irradiation | Gamma | High | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
E-beam | High | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
UV | Medium | ✓ | ✓ | ||||||
Plasma | Plasma | High | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Chemical sterilization | EtO | High | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Peracetic acid | High | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
Ethanol | Medium | ✓ | ✓ | ✓ | ✓ | ||||
Iodine | Medium | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
Novel techniques | sCO2 | ✓ | ✓ | ✓ | ✓ | ||||
Antibiotics | Low | ✓ | |||||||
Freeze-drying |
UV: ultraviolet; EtO: ethylene oxide; sCO2: supercritical carbon dioxide.