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. Author manuscript; available in PMC: 2017 May 23.
Published in final edited form as: Vaccine. 2016 Apr 19;34(24):2713–2721. doi: 10.1016/j.vaccine.2016.04.027

Figure 4. Vaccine-induced anti-V3 antibodies in buccal secretions.

Figure 4

(A) A comparison of buccal secretions collected at the different time points from each animal. ELISA was used to test undiluted samples for binding to the biotinylated cognate V3 mimotope peptides 447 and VH5-51. Secretions from four macaques collected prior to immunization (week –2) provided a negative control. Statistics: Two-Way ANOVA taking into account multiple comparisons over time with Bonferroni correction. GraphPad Prism, v6; ***p<0.0001, **p<0.01, *p=0.01. (B) Correlation between plasma and buccal secretions anti-V3 Abs in animals immunized with C4-447 and (C) C4-VH5-51, as determined using Spearman correlation coefficient (r) with p-values (two-tailed) and linear regression.