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. 2016 Mar 4;127(20):2489–2497. doi: 10.1182/blood-2015-12-688895

Figure 1.

Figure 1

Abnormal cTFH values and CXCL13 levels in patients with active cGVHD. (A) Frequency of cTFH (CXCR5+CD45RA− within CD4+ T cells) in healthy donors (HD), patients with no cGVHD, active cGVHD, and resolved cGVHD. (B) Absolute number of cTFH (CXCR5+CD45RA−CD4+ T cells) in the different clinical groups. (C) CXCL13 plasma concentration (pg/mL) was measured by ELISA and plotted for each patient group. Data were log10 transformed. Black bar represents median value for each group. The Wilcoxon rank-sum test was used. *P < .05; **P < 10−4. ns, not significant.