. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: Clin Lymphoma Myeloma Leuk. 2015 Feb 11;15(7):420–427. doi: 10.1016/j.clml.2015.02.001

Table I.

Patients with +12 by FISH and/or CBA^*

Patients (N=250)	Number (%)

FISH+/CBA−	100 (40)
FISH+/CBA+	91 (36)
FISH+ only	59 (24)

FISH +12: alone	206 (82)
with del(13q)	44 (18)

FISH +12: 7–25%	56 (22)
26–50%	86 (34)
51–75%	94 (38)
76–100%	14 (6)

CBA: diploid	93/191 (47)
+12 alone	40/191 (21)
with +19	14/191 (7)
with del(14q)	9/191 (5)
with +18	6/191 (3)
others^§	29/191 (17)

Cases were classified using the hierarchical risk model of FISH anomalies; thus cases with concomitant del(11q) or del(17p) were not included in the analysis.

^§

Additional chromosomal abnormalities associated with +12 identified by CBA and with a frequency <3% included +8, del13q and t(14;19)(q32;q13).

Abbreviations: FISH, fluorescence in situ hybridization; CBA, chromosome banding analysis.