Table 2.
Cox regression of overall survival
| N | Multivariate Step down procedure |
||
|---|---|---|---|
| HR | 95% CI | ||
| Sex | |||
| Male | 584 | Ref | – |
| Female | 1073 | 0.819 | (0.716, 0.936) |
| Age, years | |||
| <60 | 343 | Ref | – |
| 60–69 | 580 | 0.971 | (0.813, 1.161) |
| 70–79 | 521 | 1.097 | (0.915, 1.315) |
| ≥80 | 209 | 1.568 | (1.247, 1.972) |
| Unknown | 4 | 0.716 | (0.100, 5.146) |
| Histology | |||
| Ad | 1577 | Ref | – |
| Other | 80 | 2.000 | (1.512, 2.646) |
| EGFR mutation type | |||
| Del19 only | 814 | Ref | – |
| L858 only | 667 | 1.093 | (0.952, 1.254) |
| Del19 + L858R | 7 | 1.636 | (0.518, 5.159) |
| Other | 169 | 1.381 | (1.123, 1.698) |
| Clinical stage | |||
| IIIB | 125 | Ref | – |
| IV | 1105 | 1.984 | (1.535, 2.565) |
| Recurrent | 427 | 1.017 | (0.765, 1.351) |
| Performance status | |||
| 0 | 654 | Ref | – |
| 1 | 681 | 1.514 | (1.308, 1.752) |
| 2 | 117 | 2.982 | (2.326, 3.822) |
| 3 | 81 | 4.198 | (3.169, 5.561) |
| 4 | 12 | 3.179 | (1.491, 6.778) |
| Unknown | 112 | 1.020 | (0.765, 1.360) |
HR, hazard ratio; CI, confidential interval; Ad, adenocarcinoma.