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. 2016 May 15;143(10):1663–1673. doi: 10.1242/dev.136358

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© 2016. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Blimp1 expression is restricted to the luminal cell compartment of the developing mammary gland. (A) Blimp1 immunohistochemical staining of mammary gland tissue during pregnancy (P6.5, P12.5 and P18.5) and at day 1 of lactation and day 5 of involution. During pregnancy, lactation and involution, Blimp1⁺ cells are confined to the luminal cell compartment of alveolar structures (arrowheads). (B) Cryosections from 5- and 10-week-old virgins and P18.5 Blimp1-Venus (BV) mammary glands stained for GFP (green) and Krt8 (K8; red) or Krt14 (K14; red). Blimp1-expressing cells (green) are Krt8⁺ and Krt14⁻. High-magnification images of the boxed areas are shown to the right of each image. Scale bars: 50 μm.