TABLE I.
De novo AIH (n=21) |
LTC (n=27) |
HC (n=28) |
P value | |
---|---|---|---|---|
Age at blood draw mean ± SD (years) |
14.87 ± 4.60 | 10.48 ± 6.24 | 8.98 ± 5.28 | HC vs. LTC 0.3 HC vs. DAIH 0.002 LTC vs. DAIH 0.04 |
Gender (m/f) | 11/10 | 18/9 | 13/15 | 0.3 |
Duration from transplant at blood draw mean ± SD (days) |
4149.76 ± 1938.75 |
3261.80 ± 2363.39 |
n/a | 0.2 |
Duration from transplant at de novo diagnosis mean ± SD (days) |
2142.65 ± 1175.85 |
n/a | n/a | |
Pre transplant diagnosis: Biliary atresia Other |
13 8 |
17 10 |
n/a | 0.9 |
CNI trough level at blood draw mean ± SD ( ) |
4.74 ± 1.88 | 3.39 ± 2.75 | n/a | 0.2 |
AIH: Autoimmune hepatitis
LTC: Liver transplanted control
HC: Healthy control
CNI: Calcineurin inhibitor