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. 2016 May 12;3(2):ENEURO.0038-16.2016. doi: 10.1523/ENEURO.0038-16.2016

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Copyright © 2016 Gray and Golowasch

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — The CaMKII inhibitor KN-93 reduces I_MI voltage dependence. Proctolin-induced I_MI at different concentrations of KN-93. For statistical analysis, KN-93 was grouped into a low-dose (2-5 μm) and a high-dose (10-20 μm) group, in addition to a control group (0 μm). A, Representative I–V curves for a KN-93 experiment. B, Averaged I–V curves for all KN-93 experiments. C, Quantification of data shown in B. A one-way repeated-measures ANOVA showed that KN-93 significantly increased proctolin-induced I_MI slope (F_(2,5) = 46.239, p = 5.96 × 10^−4w). Recordings are from LP neurons.