Table 4. Association between BMI, serum lipid levels and dyslipidaemia and the probability of different levels of AST/ALT ratio1,2,3.
AST/ALT ratio | ||||
---|---|---|---|---|
T1 (n = 152) | T2 (n = 108) | T3 (n = 154) | P | |
Gender- and age- BMI (kg/m2), ≥25 vs. <25 (ref.) | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.44 (0.24–0.81)** | 0.43 (0.25–0.74)** | 0.003 |
2Additionally adjusted | ― | ― | ― | ― |
IFG (mg/dL), ≥100 vs. <100 (ref.) | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.53 (0.18–1.55)ns | 0.51 (0.20–1.33)ns | 0.294 |
2Additionally adjusted | 1.00 (ref.) | 0.61 (0.21–1.83)ns | 0.59 (0.22–1.57)ns | 0.494 |
TChol (mg/dL), ≥200 vs. <200 (ref.) | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.61 (0.31–1.17)ns | 0.40 (0.21–0.76)** | 0.017 |
2Additionally adjusted | 1.00 (ref.) | 0.60 (0.31–1.17)ns | 0.39 (0.20–0.75)** | 0.017 |
LDL-chol (mg/dL), ≥130 vs. <130 (ref.) | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.41 (0.19–0.88)* | 0.25 (0.11–0.55)** | 0.001 |
2Additionally adjusted | 1.00 (ref.) | 0.42 (0.19–0.91)* | 0.26 (0.12–0.57)** | 0.002 |
Non-HDL-chol (mg/dL), ≥145 vs. <145 (ref.) | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.43 (0.23–0.78)** | 0.33 (0.19–0.58)*** | <0.001 |
2Additionally adjusted | 1.00 (ref.) | 0.46 (0.25–0.85)* | 0.36 (0.20–0.63)*** | 0.001 |
HDL-chol (mg/dL), ≤40 vs. >40 (ref.) | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.42 (0.23–0.74)** | 0.41 (0.24–0.68)** | 0.001 |
2Additionally adjusted | 1.00 (ref.) | 0.48 (0.26–0.86)* | 0.47 (0.27–0.80)** | 0.007 |
TG (mg/dL), ≥100/130 vs. <100/130 (ref.)3 | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.46 (0.28–0.78)** | 0.23 (0.14–0.38)*** | <0.001 |
2Additionally adjusted | 1.00 (ref.) | 0.51 (0.30–0.87)* | 0.25 (0.15–0.42)*** | <0.001 |
RPL-chol (mg/dL), ≥24.8/27.0 vs. <24.8/27.0 (ref.)4 | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.29 (0.16–0.54)*** | 0.21 (0.12–0.37)*** | <0.001 |
2Additionally adjusted | 1.00 (ref.) | 0.33 (0.18–0.60)*** | 0.23 (0.13–0.41)*** | <0.001 |
No. dyslipidaemia components, ≥1 vs. <1 (ref.) | ||||
1Gender- and age-adjusted | 1.00 (ref.) | 0.35 (0.21–0.59)*** | 0.27 (0.17–0.44)*** | <0.001 |
2Additionally adjusted | 1.00 (ref.) | 0.37 (0.22–0.63)*** | 0.29 (0.18–0.48)*** | <0.001 |
Abbreviations: OR, odds ratio; CI, confidence interval; BMI, body mass index; IFG, impaired fasting glucose; TChol, total cholesterol; LDL-chol, low-density lipoprotein cholesterol; HDL-chol, high-density lipoprotein cholesterol; non-HDL-chol, non-high-density lipoprotein cholesterol; TG, tryglicerides; RLP-chol, remnant-like particle cholesterol.
1,2 Logistic regression analysis considering the effect of one explanatory variable after adjustment for childrens’ 1gender and age (continuous variable), and 2BMI (continuous variable).
3 TG levels were categorised as <100 or ≥100 in children aged ≤9 years, and as <130 or ≥130 in children aged 10 years.
4 High RLP-chol levels were defined as ≥P75 for boys (24.8 mg/dL) and girls (27.0 mg/dL) separately.
* P<0.05
** P<0.01
*** P<0.001
ns: not significant.