Table 1. Demographic and laboratory results.
Variables | HC (n = 25) | NAFL (n = 12) | NASH (n = 16) |
---|---|---|---|
Age (years) | 37 ± 10a,b | 45 ± 9a | 48 ± 12b |
Gender (% male) | 56 | 67 | 50 |
BMI (kg/m2)* | 27 (20–35)a | 28 (25–44) | 33 (24–50)a |
Waist circumference (cm)** | 90 (73–108)a | 97 (87–122) | 107 (89–120)a |
Hip circumference (cm) | 103 (87–120) | 106 (96–123) | 107 (100–123) |
Hypertension (%) | 0 | 8 | 6 |
ALT (U/L)** | 18 (7–38)a,b | 42.5 (14–116)a,c | 84 (39–168)b,c |
AST (U/L)** | 19 (12–29)a | 26 (16–53) | 46 (23–114)a |
ALP (U/L) | 64 (42–130) | 68 (40–101) | 71 (37–107) |
Glucose (mmol/L) | 4.9 (4.0–6.5) | 5.3 (4.6–11.4) | 5.7 (4.1–7.5) |
Insulin (pmol/L)* | 40 (15–244)a | 33 (15–465) | 102 (38–720)a |
HOMA-IR* | 1.3 (0.5–7.6)a | 1.6 (0.6–15.6) | 4.3 (1.2–40.0)a |
Hemoglobin A1c %* | 5.1 (4.4–7.2)a,b | 5.3 (0.1–5.8)a | 5.9 (5.3–7.3)b |
Triglycerides (mmol/L)* | 0.9 (0.5–3.3)a | 0.9 (0.6–1.8)b | 1.8 (0.8–5.9)a,b |
Total cholesterol (mmol/L) | 5.05 (3.57–6.69) | 5.64 (3.88–7.03) | 4.64 (2.65–9.83) |
High density lipoprotein (HDL) (mmol/L) | 1.2 (0.8–2.0) | 1.3 (1.0–1.7) | 1.1 (0.3–1.5) |
Low density lipoprotein (LDL) (mmol/L)* | 3.2 (1.9–4.7) | 3.8 (2.2–5.1)a | 2.8 (1.3–4.2)a |
Energy intake (kcal/day) | 1784 (1246–2862) | 1814 (997–2504) | 1684 (737–2717) |
Fat-derived energy % | 36 (23–47) | 29 (19–41) | 32 (7–49) |
Carbohydrate-derived energy % | 47 (38–62) | 48 (41–58) | 47 (25–85) |
Weight-adjusted energy intake (kcal/kg/day)* | 24.4 (16.0–48.8)a | 22.7 (11.9–36.8) | 18.3 (7.6–35.0)a |
The values are expressed as medians (range).
* p < 0.05.
** p < 0.001.
For each comparison, identical letters indicate the groups between which the statistical difference was significant.