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. 2016 May 20;11(5):e0151829. doi: 10.1371/journal.pone.0151829

Table 1. Demographic and laboratory results.

Variables HC (n = 25) NAFL (n = 12) NASH (n = 16)
Age (years) 37 ± 10a,b 45 ± 9a 48 ± 12b
Gender (% male) 56 67 50
BMI (kg/m2)* 27 (20–35)a 28 (25–44) 33 (24–50)a
Waist circumference (cm)** 90 (73–108)a 97 (87–122) 107 (89–120)a
Hip circumference (cm) 103 (87–120) 106 (96–123) 107 (100–123)
Hypertension (%) 0 8 6
ALT (U/L)** 18 (7–38)a,b 42.5 (14–116)a,c 84 (39–168)b,c
AST (U/L)** 19 (12–29)a 26 (16–53) 46 (23–114)a
ALP (U/L) 64 (42–130) 68 (40–101) 71 (37–107)
Glucose (mmol/L) 4.9 (4.0–6.5) 5.3 (4.6–11.4) 5.7 (4.1–7.5)
Insulin (pmol/L)* 40 (15–244)a 33 (15–465) 102 (38–720)a
HOMA-IR* 1.3 (0.5–7.6)a 1.6 (0.6–15.6) 4.3 (1.2–40.0)a
Hemoglobin A1c %* 5.1 (4.4–7.2)a,b 5.3 (0.1–5.8)a 5.9 (5.3–7.3)b
Triglycerides (mmol/L)* 0.9 (0.5–3.3)a 0.9 (0.6–1.8)b 1.8 (0.8–5.9)a,b
Total cholesterol (mmol/L) 5.05 (3.57–6.69) 5.64 (3.88–7.03) 4.64 (2.65–9.83)
High density lipoprotein (HDL) (mmol/L) 1.2 (0.8–2.0) 1.3 (1.0–1.7) 1.1 (0.3–1.5)
Low density lipoprotein (LDL) (mmol/L)* 3.2 (1.9–4.7) 3.8 (2.2–5.1)a 2.8 (1.3–4.2)a
Energy intake (kcal/day) 1784 (1246–2862) 1814 (997–2504) 1684 (737–2717)
Fat-derived energy % 36 (23–47) 29 (19–41) 32 (7–49)
Carbohydrate-derived energy % 47 (38–62) 48 (41–58) 47 (25–85)
Weight-adjusted energy intake (kcal/kg/day)* 24.4 (16.0–48.8)a 22.7 (11.9–36.8) 18.3 (7.6–35.0)a

The values are expressed as medians (range).

* p < 0.05.

** p < 0.001.

For each comparison, identical letters indicate the groups between which the statistical difference was significant.