Table 1. Performance characteristics in the OVERALL evaluation of the study images.
| Randomized VC setting | Evaluator | Accuracy for the first reading | Accuracy for the second reading | Difference in accuracy (%) [95 % CI] |
| WLI | 1 | 61.7 [56.5, 66.7] | 54.3 [49.0, 59.4] | – 7.4 [– 12.5, – 2.3]1 |
| 2 | 49.1 [43.9, 54.4] | 44.6 [39.5, 49.8] | – 4.6 [– 8.8, – 0.3]1 | |
| 3 | 49.1 [43.9, 54.4] | 52.6 [47.3, 57.7] | 3.4 [0.0, 6.8]1 | |
| Globally2 | 53.3 | 50.5 | – 2.9 [– 9.2, 3.5] | |
| FICE 1 | 4 | 63.4 [58.3, 68.3] | 52.3 [47.1, 57.5] | – 11.1 [– 16.2, – 6.0]1 |
| 5 | 61.4 [56.2, 66.4] | 63.4 [58.3, 68.3] | 2.0 [– 3.3, 7.3] | |
| 6 | 44.7 [39.6, 49.9] | 75.4 [70.6, 79.6] | 30.7 [24.3, 36.7]1 | |
| Globally2 | 56.5 | 63.7 | 7.1 [– 17.0, 31.3] | |
| FICE 2 | 7 | 63.1 [58.0, 68.0] | 73.4 [68.6, 77.8] | 10.3 [5.3, 15.2]1 |
| 8 | 65.4 [60.3, 70.2] | 58.9 [53.6, 63.9] | – 6.6 [– 12.0, – 1.1]1 | |
| 9 | 75.7 [71.0, 79.9] | 79.4 [74.9, 83.3] | 3.7 [– 0.5, 7.9] | |
| Globally2 | 68.1 | 70.6 | 2.5 [– 7.1, 12.1] | |
| FICE 3 | 10 | 62.0 [56.8, 66.9 | 77.7 [73.1, 81.8] | 15.7 [10.1, 21.2]1 |
| 11 | 58.9 [53.6, 63.9] | 50.6 [45.4, 55.8] | – 8.3 [– 14.2, – 2.2]1 | |
| 12 | 52.6 [47.3, 57.7] | 59.7 [54.5, 64.7] | 7.1 [1.3, 12.9]1 | |
| Globally2 | 57.8 | 62.7 | 4.9 [– 8.9, 18.6] | |
| Blue Mode | 13 | 36.9 [32.0, 42.0] | 62.3 [57.1, 67.2] | 25.4 [19.1, 31.4]1 |
| 14 | 71.7 [66.8, 76.2] | 77.1 [72.5, 81.2] | 5.4 [1.0, 9.8]1 | |
| 15 | 68.0 [62.9, 72.7] | 76.3 [71.6, 80.4] | 8.3 [3.3, 13.3]1 | |
| Globally2 | 58.9 | 71.9 | 13.0 [0.8, 25.3]1 |
VC, virtual chromoendoscopy; WLI, white light image; CI, confidence interval
1
statistically significant
2
stratified McNemar test