Table 2. Performance characteristics in the evaluation of the TRUE ULCERATIVE image set.

Randomized VC setting	Evaluator	Accuracy for the first reading	Accuracy for the second reading	Difference in accuracy (%) [95 % CI]
WLI	1	56.4 [50.2, 62.4]	44.0 [38.0, 50.2]	– 12.4 [– 18.4, – 6.2]1
	2	34.8 [29.2, 40.9]	29.2 [23.9, 35.1]	– 5.6 [– 11.0, – 0.2]1
	3	38.8 [33.0, 45.0]	38.0 [32.2, 44.2]	– 0.8 [– 4.4, 2.8]
	Globally2	43.3	37.1	– 6.3 [– 12.9, 0.3]
FICE 1	4	49.6 [43.5, 55.8]	33.6 [28.0, 39.7]	– 16.0 [– 22.8, – 9.0]1
	5	52.8 [46.6, 58.9]	59.2 [53.0, 65.1]	6.4 [0.0, 12.7]1
	6	32.1 [26.6, 38.2]	80.7 [75.4, 85.1]	48.6 [41.4, 54.9]1
	Globally2	44.9	57.8	12.9 [– 24.1, 50.0]
FICE 2	7	54.4 [48.2, 60.5]	69.2 [63.2, 74.6]	14.8 [8.7, 20.7]1
	8	54.8 [48.6, 60.9]	44.4 [38.4, 50.6]	– 10.4 [– 17.5, – 3.1]1
	9	90.0 [85.7, 93.1]	91.6 [87.5, 94.4]	1.6 [– 2.6, 5.9]
	Globally2	66.4	68.4	2.0 [– 12.3, 16.3]
FICE 3	10	53.2 [47.0, 59.3]	79.2 [73.7, 83.8]	26.0 [19.4, 32.2]1
	11	51.2 [45.0, 57.3]	41.6 [35.7, 47.8]	– 9.6 [– 16.7, – 2.4]1
	12	44.8 [38.8, 51.0]	46.4 [40.3, 52.6]	1.6 [– 5.5, 8.7]
	Globally2	49.7	55.7	6.0 [– 14.6, 26.6]
Blue Mode	13	12.8 [9.2, 17.5]	58.4 [52.2, 64.3]	45.6 [39.0, 51.6]1
	14	62.4 [56.3, 68.2]	77.2 [71.6, 82.0]	14.8 [9.9, 19.7]1
	15	68.0 [62.0, 73.5]	75.2 [69.5, 80.1]	7.2 [1.5, 12.8]1
	Globally2	47.7	70.3	22.5 [– 0.5, 45.5]3

VC, virtual chromoendoscopy; WLI, white light image; CI, confidence interval

¹statistically significant

²stratified McNemar test

³p = 0.07