Table 3. Analysis of patients undergoing colonoscopy with and without sedation.
Factor | Sedation (SC) n = 1500 | No Sedation (NSC) n = 194 | OR [CI] | P value | |||
Age (years) | 64 (14) | 63 (15) | – | 0.283 | |||
Time taken (minutes) | 29 (13) | 32 (18) | – | 0.590 | |||
Sex | Male | 694 (46) | 119 (61) | < 0.001 | |||
Female | 806 (54) | 75 (39) | |||||
Number | % | Number | % | ||||
Referral | Routine | 922 | 62 | 101 | 52 | – | 0.026 |
Urgent | 558 | 37 | 88 | 45 | |||
Unknown | 20 | 1 | 5 | 3 | |||
Hospital | A | 539 | 36 | 96 | 49 | – | < 0.0001 |
B | 491 | 33 | 63 | 33 | |||
C | 470 | 31 | 35 | 18 | |||
ASA | 1 | 438 | 29 | 28 | 14 | – | 0.0003 |
2 | 448 | 30 | 56 | 29 | |||
3 | 478 | 32 | 85 | 44 | |||
4 | 113 | 8 | 22 | 11 | |||
Unknown | 23 | 1 | 3 | 2 | |||
Therapeutic | 385 | 26 | 40 | 21 | 0.8 [0.5 – 1.1] | 0.128 | |
Inpatient | 673 | 45 | 84 | 43 | 0.9 [0.7 – 1.3] | 0.680 | |
Screening | 31 | 21 | 7 | 4 | 1.8 [0.8 – 4.1] | 0.178 | |
Surveillance | 161 | 11 | 22 | 11 | 1.1 [0.7 – 1.7] | 0.798 | |
Indication1 | Bleeding | 317 | 21 | 54 | 28 | 1.4 [1.0 – 2.0] | 0.034 |
Anemia | 125 | 8 | 6 | 3 | 0.4 [0.2 – 0.8] | 0.014 | |
CIBH | 297 | 20 | 51 | 26 | 1.4 [1.0 – 2.0] | 0.036 | |
Previous Resection(s) | 45 | 3 | 9 | 5 | 1.6 [0.8 – 3.3] | 0.225 | |
Pathology2 | Polyps | 351 | 23 | 51 | 26 | 1.2 [0.9 – 1.7] | 0.249 |
Inflammation | 115 | 8 | 6 | 3 | 0.4 [0.2 – 0.9] | 0.025 | |
Done by 2nd endoscopist | 217 | 15 | 29 | 15 | 1.0 [0.7 – 1.6] | 0.858 | |
Failed cecal intubation | 153 | 10 | 22 | 11 | 1.1 [0.7 – 1.8] | 0.624 | |
Adjusted cecal intubation | 1391 | 93 | 185 | 95 | 1.6 [0.8 – 3.2] | 0.180 | |
Discomfort | None | 521 | 35 | 84 | 43 | – | < 0.001 |
Minimal | 529 | 35 | 57 | 29 | |||
Mild | 269 | 18 | 25 | 13 | |||
Moderate | 150 | 10 | 9 | 5 | |||
Severe | 0 | 0 | 0 | 0 | |||
Unrecorded | 31 | 2 | 19 | 10 | |||
Complications | 30 | 2 | 2 | 1 | – | 0.351 | |
Poorly tolerated | 25 | 2 | |||||
Damaged scope | 3 | 0 | |||||
Bleeding | 2 | 0 |
Age and time expressed as average (standard deviation). Significant values were P < 0.05, derived by Chi-square test, t-test or Mann-Whitney. Odds ratio were obtained by univariate analysis.
CIBH: change in bowel habit
Only indications with significant P values are shown
No significant differences were found for diverticular disease, strictures or radiation proctitis.