Table 3.
Changes in Annual Adherence to Medications (2006–2012)
| Pre‐2009 | Post‐2009 | p‐Value for Pre–Post Δ in Trend | |
|---|---|---|---|
| % Δ in MPR†/year [95% CI] | % Δ in MPR/year [95% CI] | ||
| Panel A: Overall employee sample† | |||
| Beta‐blockers | 0.20* [0.014, 0.39] | 0.22* [0.030, 0.41] | .08 |
| ACEIs/ARBs | 0.12* [0.0071, 0.23] | 0.15** [0.037, 0.26] | <.001 |
| Statins | 0.070 [−0.053, 0.19] | 0.095 [−0.028, 0.22] | <.001 |
| Asthma/COPD controllers | 0.14 [−0.12, 0.40] | 0.10 [−0.15, 0.36] | .03 |
| Panel B: Employees at high‐layoff plants‡ | |||
| Beta‐blockers | 0.31* [0.029, 0.59] | 0.34* [0.055, 0.62] | .02 |
| ACEIs/ARBs | 0.11 [−0.034, 0.26] | 0.15* [0.0079, 0.30] | <.001 |
| Statins | 0.10 [−0.064, 0.27] | 0.14 [−0.029, 0.30] | <.001 |
| Asthma/COPD controllers | 0.16 [−0.19, 0.51] | 0.13 [−0.22, 0.47] | .13 |
†Analyses were conducted using segmented regression with a discontinuity in 2009, with fixed effects at the individual level. Control variables included age‐squared and age‐cubed. Standard errors clustered at the individual level.
‡Analyses were conducted using segmented regression with a discontinuity in the year of each plant's first mass layoff event, with fixed effects at the individual level. Control variables included age‐squared and age‐cubed. Standard errors clustered at the individual level.
*p < .05, **p < .01.
ACEI, angiotensin‐converting enzyme inhibitors; ARB,angiotensin‐receptor blockers; COPD, chronic obstructive pulmonary disease; MPR, medication possession ratio.