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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Transplantation. 2016 Jun;100(6):1211–1218. doi: 10.1097/TP.0000000000001146

Fig 3. Effect of Encaptra™ on T cell priming by allogeneic cells.

Fig 3

Groups of B6 mice were transplanted with non-encapsulated BALB/c x B6 F1 splenocytes (naked) or BALB/c x B6 F1 splenocytes in intact or punctured Encaptra™. One day later all the mice alone with a group on non-transplanted (naïve) mice received CFSE-labeled 4C, TCR75 and 2C cells. (A) Representative histograms of CFSE dilution of 4C, TCR75 and 2C cells are shown. (B) Quantitative summary of results on A from 5 independent experiments are shown. The p values were determined using Kruskal-Wallis test followed by Dunn’s multiple comparisons test (4C: Naked vs. Intact device p=0.04; TCR75: Naked vs. Intact device p=0.005, Intact device vs. Punctured device p=0.04; 2C: Naked vs. Intact device p<0.05, Intact device vs. Punctured device p=0.04).