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(A) Parental UBPs (d)5SICS-(d)MMO2) and (d)5SICS-(d)NaM. (B) Previously identified linker-derivatized unnatural nucleotides 5SICSATP and MMO2ATP. (C) Linker-derivatized analogs synthesized and characterized in this study, 5SICSCOTP, NaMATP, and NaMCOTP. Phosphates and ribose not shown.
