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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Hepatology. 2016 Mar 25;63(6):1900–1913. doi: 10.1002/hep.28508

Figure 8.

Figure 8

Ablation of CD36 does not affect AKT/NICD driven cholangiocarcinogenesis. (A) Study design: activated forms of AKT and NICD1 were hydrodynamically injected into CD36 knockout (CD36KO) mice (n=5). (B) Macroscopically (macro), livers from AKT/NICD injected CD36KO mice showed the presence of multiple cysts. (C) Microscopically, cysts consisted of ICC that were indistinguishable from those developed in AKT/NICD injected wild-type mice. Original magnification: 100X in upper panels; 200X in lower panels. Abbreviation: HE, hematoxylin and eosin staining.