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. Author manuscript; available in PMC: 2017 May 20.
Published in final edited form as: ACS Chem Biol. 2016 Feb 19;11(5):1238–1244. doi: 10.1021/acschembio.5b01002

Figure 2.

Figure 2

Sequence logos for populations of peptides from library LA screening. 96 Mcl-1 specific stapled peptides were identified from competition screens using a mixture of BioMcl-1:mycBcl-xL (1:50). 77 Bcl-xL-specific peptides were identified in competition screening using BioBcl-xL:mycMcl-1 (1:50). The side chains at the 3c and 3g positions, marked X, were replaced with cross-linked α-4-pentenylalanine groups. Mutations were made at positions 2d, 2e, 2g, 3b, 3e, 4a and 4e. Figures were made using WebLogo.