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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Menopause. 2016 Jun;23(6):626–637. doi: 10.1097/GME.0000000000000597

TABLE 2.

VMS change in frequency by week from baseline and comparisons between groups and from baseline

Acupuncture
 Control
 P-values
Week Na Change in VMS Estimatesb Na Change in VMS Estimatesb Acupuncture vs Control Acupuncture vs no change Control vs no change
1 167 −10.2 (3.7) 39 −1.2 (7.7) 0.29 0.006 0.87
2 168 −18.4 (3.7) 39 −3.6 (7.7) 0.08 <.001 0.64
3 169 −23.7 (3.7) 38 −2.4 (7.7) 0.01 <.001 0.75
4 168 −27.9 (3.7) 37 2.5 (7.8) <.001 <.001 0.75
5 165 −30.5 (3.7) 36 −1.2 (7.9) <.001 <.001 0.88
6 164 −32.7 (3.7) 36 −0.2 (7.9) <.001 <.001 0.98
7 162 −34.2 (3.7) 36 −1.9 (7.9) <.001 <.001 0.81
8 163 −33.9 (3.7) 35 −3.3 (7.9) <.001 <.001 0.68
9 160 −29.5 (3.7) 35 −0.6 (7.9) 0.001 <.001 0.94
10 159 −29.6 (3.7) 35 1.3 (7.9) <.001 <.001 0.87
11 156 −31.6 (3.8) 34 −0.8 (8.0) <.001 <.001 0.92
12 155 −33.0 (3.8) 35 −5.3 (7.9) 0.002 <.001 0.51
13 153 −31.0 (3.8) 36 −2.3 (7.9) 0.001 <.001 0.77
14 154 −35.3 (3.8) 36 −0.3 (7.9) <.001 <.001 0.97
15 152 −34.1 (3.8) 36 −3.5 (7.9) <.001 <.001 0.65
16 153 −36.1 (3.8) 36 −6.0 (7.9) <.001 <.001 0.44
17 151 −37.5 (3.8) 35 −7.6 (7.9) <.001 <.001 0.34
18 151 −36.2 (3.8) 35 −9.2 (7.9) 0.002 <.001 0.25
19 150 −34.4 (3.8) 35 −5.3 (7.9) <.001 <.001 0.50
20 149 −35.8 (3.8) 35 −3.7 (7.9) <.001 <.001 0.64
21 150 −35.5 (3.8) 35 −1.9 (7.9) <.001 <.001 0.81
22 149 −36.5 (3.8) 35 −3.3 (7.9) <.001 <.001 0.67
23 145 −34.7 (3.8) 34 −0.7 (8.0) <.001 <.001 0.93
24 147 −34.6 (3.8) 35 3.3 (7.9) <.001 <.001 0.68
25 145 −34.3 (3.8) 33 2.2 (8.0) <.001 <.001 0.78
26 139 −36.7 (3.9) 33 6.0 (8.0) <.001 <.001 0.46
End of treatment for acupuncture group and start of treatment for control group
27-30 142 −31.3 (3.2) 35 −1.9 (6.7) <.001 <.001 0.78
31-34 143 −25.7 (3.4) 34 −16.6 (7.3) 0.26 <.001 0.02
35-38 140 −27.9 (3.4) 33 −18.0 (7.0) 0.20 <.001 0.01
39-42 141 −31.9 (3.4) 34 −24.6 (7.0) 0.35 <.001 <.001
43-46 141 −30.8 (3.4) 33 −21.5 (7.3) 0.25 <.001 0.003
47-50 138 −31.0 (3.4) 33 −25.5 (7.0) 0.48 <.001 <.001
51-54 115 −29.5 (3.6) 29 −31.0 (7.3) 0.85 <.001 <.001

VMS, vasomotor symptoms.

a

Number of participants with a diary in a given period.

b

Adjusted for baseline VMS, season of randomization, site, acupuncture use prior to the study, use of hormone therapy, and baseline menopause status.