FIG. 6.

Cost function design. (a) Histogram H of a region around a typical lesion with corresponding envelope function $\tilde{H}$. (b) Example of a cost function; the individual components are clearly visible. The left part follows $\tilde{H}$, while the right part is linear. The lowest point where both parts meet is at Th. (c) Example of a typical cost profile with and without c_reject on a single column i, as a function of j, paired with the uptake along the column.