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The management of a study subject. a An extensive early esophageal neoplasm viewed using chromoendoscopy and iodine staining. b A full circumferential mucosal defect immediately after endoscopic submucosal dissection (ESD). c Preparation of carboxymethyl cellulose (CMC) sheets. d CMC sheet pulled into the cap with a biopsy forcep. e Application of CMC sheets. f Defect appearance immediately after CMC sheets placement
