Table 3.
Risk class | n | Events | Incidence rate a | Hazard ratio |
---|---|---|---|---|
Derivation cohort | ||||
Low (<1%) | 4170 | 46 | 0.56 (0.41, 0.74) | 1.00 (ref) |
Medium (1–2%) | 7154 | 187 | 1.37 (1.18, 1.58) | 2.45 (1.78, 3.38) |
High (>2%) | 3377 | 158 | 2.63 (2.24, 3.08) | 4.67 (3.36, 6.48) |
Validation cohort | ||||
Low (<1%) | 820 | 16 | 0.56 (0.32, 0.90) | 1.00 (ref) |
Medium (1–2%) | 448 | 19 | 1.29 (0.78, 2.02) | 2.34 (1.20, 4.55) |
High (>2%) | 132 | 13 | 3.22 (1.71, 5.50) | 5.80 (2.79, 12.1) |
a Per 100 person-years.