Table 1. Selection Analysis for the Capsid Protein of HEV (Sequences Isolated From Humans).
Analysis | Site |
---|---|
Negatively selected sites a (w for sites < 1) HYPHY software | 1994 (V); 1996(L,F); 1997(C,F); 1998(I); 2000(G); 2001(S); 2002(P); 2003(N); 2004(S); 2005(Y); 2006(T); 2007(N,Y); 2008(T); 2009(P);2010(Y); 2011(T); 2014(A); 2015(L); 2016(G); 2017(L); 2019(D); 2020(A); 2021(L); 2022(E,G); 2023(L); 2024(E); 2025(R); 2026(N); 2027(L); 2028(P); 2034(T); 2036(T); 2038(V); 2040(R); 2042(T,S); 2043(S); 2044(T); 2045(A); 2046(R); 2047(H); 2048(R); 2049(L); 2050 (R); 2051(R); 2052(G); 2053(A); 2054(D); 2055(G); 2056(T); 2057(A); 2058(E); 2059(L); 2060(T); 2061(T); 2062(T); 2063(A); 2065(T); 2066(R); 2067(F); 2069(K); 2070(D); 2071(L); 2072(H); 2073(F); 2075(G); 2076(T,M); 2077(N); 2078(G); 2079(V); 2080(G); 2082(V); 2085(G); 2086(I); 2087(A); 2088(L); 2089(T,I); 2090(L); 2091(F); 2092(N); 2095D); 2096(T); 2098(L); 2099(G); 2100(G); 2101 (L); 2105(L); 2108(S). |
aNegatively selected sites are numbered according to the amino acid position of the capsid protein of HEV isolate accession number AB369687.1