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. Author manuscript; available in PMC: 2017 May 19.
Published in final edited form as: Mol Cell. 2016 May 19;62(4):507–519. doi: 10.1016/j.molcel.2016.04.014

Figure 6. Negative Association of UVRAG Expression Z-score with UV-like Mutagenesis in Skin Melanoma.

Figure 6

(A and B) UVRAG expression Z-score in samples with high (> 50%) and low (≤ 50%) C>T/G>A transitions at dipyrimidines (A) and at non-dipyrimidines (B) for 340 available skin cutaneous melanoma (SKCM) TCGA primary tumors. Note the inverse relationship between UVRAG expression and C>T/G>A transition at dipyrimidines (A), but the absence of such a relationship at non-dipyrimidines (B). p, two-sided Wilcoxon rank-sum test.

(C and D) UVRAG expression Z-score in samples with high (> 50%) and low (≤ 50%) C>T/G>A transitions at dipyrimidines (C) and at non-dipyrimidines (D) for uveal melanoma (UVM) TCGA primary tumors (n = 80). p, two-sided Wilcoxon rank-sum test.

See also Figure S7 for additional information.