Table 1.
Patient characteristics
| Patients without intradialytic hypotension (n = 26) |
Patients with intradialytic hypotension (n = 13) |
p value | |
|---|---|---|---|
| Age (years) | 63 [49–69] | 63 [54–80] | 0.17 |
| Male gender (no, %) | 17 (65 %) | 8 (59 %) | 0.99 |
| Simplified Acute Physiology Score II | 41 [46–55] | 49 [45–53] | 0.49 |
| Previous chronic renal failure (no, %) | 10 (40 %) | 5 (38 %) | 0.82 |
| Previous chronic arterial hypertension (no, %) | 8 (30 %) | 5 (40 %) | 0.79 |
| Aetiology of acute circulatory failure (no, %) | |||
| Septic | 20 (77 %) | 10 (77 %) | 0.69 |
| Cardiogenic | 6 (23 %) | 3 (23 %) | 0.69 |
| Incidence of shock diagnosis criteria at the initial phase | |||
| Systolic arterial pressure <90 mmHg | 26 (100 %) | 13 (100 %) | – |
| Decrease >50 mmHg in previously hypertensive patients | 0 (0 %) | 1 (8 %) | 0.68 |
| Need for norepinephrine administration | 26 (100 %) | 13 (100 %) | – |
| Urine output <0.5 mL/kg/h for at least 2 h | 26 (100 %) | 12 (92 %) | 0.68 |
| Heart rate >100 beats/min | 20 (77 %) | 13 (100 %) | 0.16 |
| Skin mottling | 8 (31 %) | 6 (46 %) | 0.57 |
| Blood lactate >2 mmol/L | 26 (100 %) | 11 (85 %) | 0.21 |
| Left ventricular ejection fraction (%) | 50 [30–60] | 45 [35–52] | 0.57 |
| Modalities of ventilation | |||
| Invasive mechanical ventilation (no, %) | 11 (42 %) | 6 (46 %) | 0.91 |
| Tidal volume (mL/kg) | 6 [6–7] | 7 [6–7] | 0.34 |
| PEEP (cmH2O) | 7 [6–10] | 7 [7–11] | 0.22 |
| Plateau pressure (cmH2O) | 17 [16–19] | 18 [16–24] | 0.31 |
| Respiratory rate (min−1) | 20 [15–20] | 20 [20–21] | 0.71 |
| Non-invasive mechanical ventilation (no, %) | 6 (23 %) | 0 (0 %) | 0.16 |
| No mechanical ventilation (no, %) | 9 (35 %) | 7 (54 %) | 0.43 |
| Acute respiratory distress syndrome (no, %) | 10 (38 %) | 6 (46 %) | 0.89 |
| Blood urea nitrogen (mmol/L) | 32 [28–34] | 30 [29–31] | 0.25 |
| Patients receiving norepinephrine (no, %) | 9 (35 %) | 7 (54 %) | 0.43 |
| Dose of norepinephrine (µg/kg/min) | 0.15 [0.04–0.25] | 0.24 [0.21–0.32] | 0.69 |
| Lactate (mmol/L) | 1.1 [0.9–1.1] | 0.9 [0.9–1.1] | 0.38 |
| Days in the ICU before inclusion (days) | 13 [6–28] | 11 [5–18] | 0.67 |
Values are expressed as median [interquartile range] or number and frequency in %
There was no significant difference between patients with and patients without intradialytic hypotension
PEEP positive end-expiratory pressure; RRT renal replacement therapy