Table 3.
TLR2, TLR4 and NOD2 polymorphisms in bipolar patients and healthy controls: genotype distribution
| Polymorphism | MAF | p value | HWE p value | ||
|---|---|---|---|---|---|
| BD (n = 138) | Controls (n = 167) | ||||
| TLR2 rs4696480 | T > A | 0.46 | 0.51 | 0.178 | 0.929 |
| TLR2 rs3804099 | T > C | 0.46 | 0.44 | 0.610 | 0.804 |
| TLR4 rs1927914 | A > G | 0.41 | 0.39 | 0.601 | 0.671 |
| TLR4 rs11536891 | T > C | 0.17 | 0.14 | 0.265 | 0.588 |
| NOD2 rs2066842 | C > T | 0.25 | 0.25 | 0.898 | 0.656 |
TLR2 Toll-like receptor 2; TLR4 Toll-like receptor 4; NOD2 nucleotide-binding oligomerization domain containing 2; BD bipolar disorder; NS non-significant; MAF minor allele frequency; HWE Hardy–Weinberg equilibrium in controls