Table 3.
Correlation between week-36 discordance and measurements of disease at baseline and week 36, and change from baseline to week 36
| Baseline | Week 36 | Change baseline to week 36 | ||||
|---|---|---|---|---|---|---|
| Number | Pearson’s r | Number | Pearson’s r | Number | Pearson’s r | |
| DAS28 | 760 | −0.0225 | 762 | 0.1832*** | 760 | 0.1942*** |
| CRP | 754 | −0.0561 | 756 | −0.0097 | 754 | 0.0523 |
| ESR | 763 | −0.0630 | 763 | 0.0287 | 763 | 0.0924* |
| TJC | 760 | 0.0058 | 762 | 0.0449 | 760 | 0.0269 |
| SJC | 760 | −0.1197** | 762 | −0.0662 | 760 | 0.0678 |
| Duration of morning joint stiffness | 745 | 0.0813* | 747 | 0.1456*** | 745 | −0.0094 |
| BPI | 753 | 0.2268*** | 761 | 0.4784*** | 753 | 0.1854*** |
| HAQ-DI | 757 | 0.0648 | 762 | 0.3174*** | 757 | 0.2404*** |
| FACIT-fatigue | 753 | −0.1437*** | 761 | −0.3645*** | 753 | −0.2054*** |
| CDAI | 760 | 0.0116 | 762 | 0.1986*** | 760 | 0.1602*** |
| SDAI | 751 | −0.0068 | 755 | 0.1912*** | 751 | 0.1698*** |
| Patient general health VAS | 762 | 0.1826*** | 763 | 0.5784*** | 762 | 0.3542*** |
| Duration of disease | 761 | −0.0402 | na | na | na | na |
Discordance is defined as patient global assessment – physician global assessment. BPI brief pain inventory, CDAI clinical disease activity index, CRP C-reactive protein, DAS28 disease activity score based on 28 joint count, ESR erythrocyte sedimentation rate, FACIT-fatigue functional assessment of chronic illness therapy-fatigue, HAQ-DI health assessment questionnaire disability index, na not available, SDAI simplified disease activity index, SJC swollen joint count, TJC tender joint count, VAS visual analog scale. *p < 0.05, **p < 0.001, ***p < 0.0001