Table 2.
Percent density, overall and for women age 50+ at mammogram
| Quintile group | Frequency | Model 1a | Model 2b | Model 3c | ||||
|---|---|---|---|---|---|---|---|---|
| Case | Control | OR | 95 % CI | OR | 95 % CI | OR | 95 % CI | |
| Percent density, overall (297 cases and 1149 controls) | ||||||||
| Q1: 6.08 or less | 40 | 229 | 1.00 | Ref | 1.00 | Ref | 1.00 | Ref |
| Q2: 6.09–11.94 | 49 | 230 | 1.41 | 0.87–2.29 | 1.41 | 0.86–2.29 | 1.49 | 0.91–2.45 |
| Q3: 11.95–20.04 | 60 | 230 | 2.37 | 1.44–3.89 | 2.38 | 1.44–3.91 | 2.57 | 1.54–4.30 |
| Q4: 20.05–31.56 | 69 | 230 | 3.08 | 1.87–5.06 | 2.95 | 1.79–4.88 | 3.22 | 1.91–5.43 |
| Q5: 31.57+ | 79 | 230 | 4.45 | 2.62–7.56 | 4.36 | 2.55–7.43 | 4.88 | 2.78–8.55 |
| Percent densityd | 1.66 | 1.39–1.97 | 1.64 | 1.38–1.96 | 1.70 | 1.41–2.04 | ||
| Percent density, women age 50+ (288 cases and 1116 controls) | ||||||||
| Q1: 6.07 or less | 40 | 223 | 1.00 | Ref | 1.00 | Ref | 1.00 | Ref |
| Q2: 6.08–11.71 | 48 | 223 | 1.39 | 0.85–2.26 | 1.39 | 0.85–2.27 | 1.47 | 0.89–2.43 |
| Q3: 11.72–19.71 | 57 | 223 | 2.23 | 1.35–3.68 | 2.24 | 1.36–3.71 | 2.43 | 1.45–4.08 |
| Q4: 19.72-30.97 | 66 | 223 | 2.97 | 1.79–4.92 | 2.87 | 1.72–4.76 | 3.13 | 1.85–5.31 |
| Q5: 30.98+ | 77 | 224 | 4.22 | 2.49–7.16 | 4.16 | 2.45–7.08 | 4.65 | 2.66–8.14 |
| Percent densityd | 1.64 | 1.38–1.95 | 1.63 | 1.36–1.94 | 1.68 | 1.40–2.02 | ||
aAdjusted for matching factors (age at FFDM, laterality, density batch number), BMI (continuous), and BMI (categorical)
bAdjusted for matching factors, BMI (categorical and continuous), parity, first-degree family history, and hormone use
cAdjusted for matching factors, BMI (categorical and continuous), parity, first-degree family history, hormone use, and breast area (continuous)
dORs for square root of percent density (continuous) per standard deviation unit