Table 3.

Probabilities of APOB concentration in human FF, divided into quartiles (Q), to predict IVF/ICSI outcomes

APOB quartiles (ng/ml)	n / number of FF analyzed (%)	P	Crude OR [95 % CI]	p-value	Adjusted OR [95 % CI]a	p-value
Probabilities of obtaining an oocyte
Q1 (<112)	24/50 (48.0)	0.001	-- (reference)		-- (reference)
Q2 (≥112, <230)	40/51 (78.4)		3.9 [1.65–9.4]	0.002	3.4 [1.04–11.2]	0.044
Q3 (≥230, <330)	39/49 (79.6)		4.2 [1.73–10,3]	0.002	3.3 [1.19–9.08]	0.022
Q4 (≥330)	40/51 (78.4)		3.9 [1.65–9.4]	0.002	3.4 [1.01–11.44]	0.049
Probabilities of obtaining a fertilized oocyte
Q1(<112)	12/50 (24.0)	<0.001	-- (reference)		-- (reference)
Q2 (≥112, <230)	34/51 (66.7)		6.2 [1.79–21.76]	0.004	7.3 [1.59;33.43]	0.011
Q3 (≥230, <330)	33/49 (67.3)		10.1 [2.38–42.69]	0.002	11.2 [1.67;75.63]	0.013
Q4 (≥330)	28/51 (55.0)		6.4 [1.69–24.37]	0.006	6.3 [1.13;34.86]	0.035
Probabilities of obtaining an embryo on day 2
Q1(<112)	5/50 (10.0)	<0.001	-- (reference)		-- (reference)
Q2 (≥112, <230)	32/51 (62.8)		15.2 [5.11–44.95]	<0.001	17.3 [2.2;137.1]	0.007
Q3 (≥230, <330)	31/49 (63.3)		15.5 [5.19–46.29]	<0.001	15.5 [1.9;130.3]	0.011
Q4 (≥330)	24/51 (47.1)		8 [2.72–23.51]	<0.001	8.3 [0.8;82.0]	0.071
Probabilities of obtaining a top quality embryo on day 2
Q1(<112)	4/50 (8.0)	0.047	-- (reference)		-- (reference)
Q2 (≥112, <230)	14/51 (27.5)		4.4 [1.32–14.38]	0.016	4.8 [1.04;22.41]	0.045
Q3 (≥230, <330)	13/49 (26.5)		4.2 [1.24–13.86]	0.021	4.1 [0.75;22.64]	NS
Q4 (≥330)	14/51 (27.4)		4.4 [1.32–14.38]	0.016	3.9 [0.64;23.91]	NS

^aProbabilities to obtain an oocyte and an embryo were adjusted for age and aetiology of infertility. Probabilities to obtain a fertilized oocyte and a top embryo were adjusted for age. Q1, quartile 1; Q2, quartile 2; Q3, quartile 3; Q4, quartile 4. Q1 was considered as the reference. OR Odds Ratio, CI confidence intervals, FF Follicular Fluid, NS No significant