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. 2016 May 21;16:324. doi: 10.1186/s12885-016-2349-3

Table 3.

Clinical and Pathological Features in Nine Cases of Bladder Cancer with PNS

Case No. Author Year Age/Gender Stage Pathology Clinical syndromes Antibody Treatment Prognosis
1 Gita et al.[17] 2015 73/F Ma Poorly differentiated carcinoma with squamous features PEM Negtive Surgical resection and immunosuppression Partial improvement
2 Syuichi et al.[12] 2013 66/M N/A Urothelial carcinoma PCD Anti-CKB TURBT No improvement
3 Lukacs et al.[20] 2012 76/F pTa Urothelial carcinoma PEM and SSN Anti-Hu TURBT Partial improvement
4 Forte et al.[21] 2009 76/M pT2 High grade urothelial carcinoma Neuromyotonia Anti-VGKC Resectionofthetumour Complete improvement
5 Sean et al.[14] 2003 59/M N/A N/A POM Anti-Ri N/A N/A
6 Charles et al.[22] 2001 57/M pT3 High grade urothelial carcinoma POM Anti-Ri Radical cystectomy and immunosuppression Partial improvement
7 Lowe et al.[23] 1992 71/M pT3 High grade urothelial carcinoma Visual changes, glossal spasm and dysphagia N/A Combination chemotherapy Complete improvement
8 John et al.[11] 1999 64/F pT2 High grade urothelial carcinoma PCD Anti-Yo Partial resection of the bladder No improvement
9 Current report 2015 68/M pCIS High grade urothelial carcinoma and the well-differentiated squamous cell carcinoma PCD Negtive Laparoscopic radical cystectomy Complete improvement

aA recurrent pelvis mass proven as urothelial carcinoma 22 years after radical cystectomy; PEM Paraneoplastic encephalomyelitis; PCD Paraneoplastic cerebellar degeneration; SSN Subacute sensory neuronopathy; POM Paraneoplastic opsoclonus-myoclonus; Anti-CKB anti-creatine kinase, brain-type; N/A Not available