Table 4.
Neurologist network: demographic and clinical data pertaining to seven GBS patients with influenza immunisations during the 42-day period preceding clinical onset
| Patient ref. no., sex, age | Vaccination date and type (a) | Co-morbidity or clinical antecedent in 30 days prior to onset | Symptom onset (b) | (a-b) Interval in weeks | Functional level at one week | Treatment | Clinical confirmation on the basis of |
|---|---|---|---|---|---|---|---|
| 1 Female 53 |
2 Oct 2009 | Motor neurone disease | 13 Oct 2009 | 1–2 | Walking | Not treated | Clinical symptoms/exam. |
| 2009-TIV | Cerebrospinal fluid (CSF) tests | ||||||
| Electrophysiology lab. | |||||||
| Other causes excluded | |||||||
| 2 Male 68 |
27 Oct 2009 | Heart disease. | 22 Nov 2009 | 3–4 | Bed-bound | IVGG | Electrophysiology lab. |
| 2009-TIV | Sleep apnea. High blood pressure. Bronchopulmonary infection | Other causes excluded | |||||
| 3 Male 34 |
20 Oct 2009 | Syphilis seropositive | 30 Nov 2009 | 5–6 | Walking | IVGG | Clinical symptoms/exam. |
| 2009-TIV | CSF tests | ||||||
| Electrophysiology lab. | |||||||
| Other causes excluded | |||||||
| 4 Male 70 |
28 Sept 2009 | Motor neurone disease | 10 Oct 2009 | 1–2 | Bed-bound | IVGG | Clinical symptoms/exam |
| 2009-TIV | CSF tests | ||||||
| Electrophysiology lab. | |||||||
| Other causes excluded | |||||||
| 5 Male 77 |
18 Oct 2010 | - | 1 Nov 2010 | 2 | Bed-bound | IVGG | Clinical symptoms/exam. |
| 2010–2011-TIVa | Electrophysiology lab. Other causes excluded | ||||||
| 6 Female 78 |
5 Jan 2011 | - | 15 Jan 2011 | 1–2 | Able to walk with support | IVGG | Clinical symptoms/exam. |
| 2010–2011-TIV | CSF tests | ||||||
| Electrophysiology lab. Other causes excluded | |||||||
| 7 Male 82 |
27 Oct 2011 | High blood pressure | 23 Nov 2011 | 4 | Bed-bound | IVGG Mechanical Ventilation | Clinical symptoms/exam. |
| 2010–2011-TIVa | DM | CSF tests | |||||
| Atrial fibrillation | Electrophysiology lab. Other causes excluded |
GBS Guillain-Barré syndrome, DM diabetes mellitus type 2, TIV seasonal trivalent influenza vaccine, IVGG intravenous gammaglobulin
aReceived the vaccine Chiromas® (Novartis), adjuvanted with MF59C.1