High MCAM and LAMA4 tumour vessel expression has a significant detrimental effect on the survival of RCC patients but not CRC patients. A, representative images demonstrative of scoring for staining intensity. Images are of MCAM staining in RCC at a weak (i-ii) or strong (iii-iv) level. Scale bar = 50 μm. B, Kaplan-Meier survival analysis of patients, from RCC cohort 1,2 and 3 and the CRC cohort, with strong vs. weak staining for MCAM, LAMA4 and marker co-expression. Statistical analysis: Log-ranks test, p and n for each test are shown. Crosses mark censored cases.