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. Author manuscript; available in PMC: 2016 Oct 15.
Published in final edited form as: Cancer Res. 2016 Feb 26;76(8):2314–2326. doi: 10.1158/0008-5472.CAN-15-1364

Table 1.

Consistently upregulated vascular genes across cancer types (gene expression comparison shown as Log2 fold change).

Gene ID Gene symbol GenBank accession No. RCC vs Kidney CRC vs Colon CRM vs Colon CRM vs Liver Gene ontology
Lysyl oxidase LOX NM_002317 2.80 1.20 1.00 1.86 EX and IC
Angiopoietin 2 ANGPT2 NM_001147 2.50 3.40 2.48 1.22 EX
Laminin, alpha 4 LAMA4 NM_001105206 2.41 1.50 1.53 1.75 EX
Melanoma cell adhesion molecule MCAM NM_006500 2.38 1.70 1.43 −0.51 PM
Regulator of G-protein signaling 5 RGS5 NM_003617 2.24 2.79 1.22 −1.40 PM
Matrix metallopeptidase 1 MMP1 NM_002421 0.16 4.49 −0.57 2.12 EX
Endothelial cell-specific molecule 1 ESM1 NM_007036 0.91 2.63 1.37 −0.17 EX
Transglutaminase 2 TGM2 NM_198951 −0.32 2.60 2.36 1.54 IC and PM
Serpin peptidase inhibitor H1 SERPINH1 NM_001207014 −0.04 2.09 2.06 1.04 EX and IC
Biglycan BGN NM_001711 0.92 1.29 3.75 0.03 EX
Neuropilin 1 NRP1 NM_001024629 0.66 1.23 2.37 0.25 PM
Coagulation factor II (thrombin) receptor F2R NM_001992 1.18 1.42 2.12 1.07 PM
Troponin C type 2 (fast) TNNC2 NM_003279 −0.26 1.28 1.11 3.38 IC
Serpin peptidase inhibitor B5 SERPINB5 NM_002639 −0.33 1.12 0.35 2.82 EX
Apelin APLN NM_017413 1.34 1.98 1.20 0.30 EX
Protease, serine, 23 PRSS23 NM_007173 1.02 1.53 0.65 0.68 IC
Serpin peptidase inhibitor E1 SERPINE1 NM_000602 1.09 0.85 1.81 0.71 EX and PM
Secreted protein, acidic, cysteine-rich SPARC NM_003118 0.47 1.39 1.64 −0.10 EX
Sushi-repeat containing protein, X-linked 2 SRPX2 NM_014467 −0.62 1.22 1.11 1.92 EX and IC
Peroxidasin homolog (Drosophila) PXDN NM_012293 1.36 1.20 1.44 0.68 EX
Calcitonin receptor-like CALCRL NM_005795 1.26 1.03 1.42 −0.08 PM
Chemokine (C-C motif) ligand 20 CCL20 NM_004591 1.25 1.04 1.29 0.08 EX
Follistatin-like 1 FSTL1 NM_007085 0.69 1.48 1.44 1.03 EX
Transcription factor 4 TCF4 NM_003199 1.05 1.41 1.15 −1.02 IC
Lectin, galactoside-binding, soluble, 1 LGALS1 NM_002305 1.10 1.25 1.35 0.66 EX and IC
Vimentin VIM NM_003380 1.01 0.50 1.01 −0.89 IC and PM