Table 1.
Patient Characteristics
| Treatment Technique | Pa | ||||||
|---|---|---|---|---|---|---|---|
| 3DCRT (n = 22) | IMRT (n = 34) | PBT (n = 26) | |||||
| Age | 0.634 | ||||||
| Mean (SD) | 63.6 (9.0) | 65.7 (6.7) | 65.0 (9.2) | ||||
| Median (range) | 63.7 (42.5–77.9) | 65.6 (48.1–77.8) | 65.5 (43.0–79.0) | ||||
| BMI (kg/m2) | 0.606 | ||||||
| Mean (SD) | 26.7 (6.0) | 28.2 (5.8) | 28.1 (4.6) | ||||
| Median (range) | 25.1 (19.6–45.2) | 27.0 (19.7–42.2) | 27.3 (20.5–38.9) | ||||
| Total tumor dose (Gy RBE) | < 0.0001 | ||||||
| Mean (SD) | 62.1 (3.3) | 64.7 (6.4) | 70.6 (5.7) | ||||
| Median (range) | 63.0 (50.4–70.0) | 63.0 (41.4–70.0) | 74.0 (54.0–74.0) | ||||
| n | % | n | % | n | % | ||
| Sex | 0.846 | ||||||
| Male | 10 | 45.45 | 17 | 50.00 | 14 | 53.85 | |
| Female | 12 | 54.55 | 17 | 50.00 | 12 | 46.15 | |
| Race | 0.920 | ||||||
| Non-Hispanic white | 19 | 86.36 | 28 | 82.35 | 22 | 84.62 | |
| Other | 3 | 13.64 | 6 | 17.65 | 4 | 15.38 | |
| Marital status | 0.893 | ||||||
| Married | 15 | 68.18 | 25 | 73.53 | 18 | 69.23 | |
| Unmarried | 7 | 31.82 | 9 | 26.47 | 8 | 30.77 | |
| Education | 0.216 | ||||||
| College or higher | 10 | 45.45 | 15 | 44.12 | 17 | 65.38 | |
| High school or lower | 12 | 54.55 | 19 | 55.88 | 9 | 34.62 | |
| Cancer stage | 0.108 | ||||||
| I/II | 2 | 9.09 | 10 | 29.41 | 8 | 34.78 | |
| III | 20 | 90.91 | 24 | 70.59 | 15 | 65.22 | |
| ECOG PS | 0.023 | ||||||
| 0–1 | 18 | 81.82 | 31 | 93.94 | 24 | 100.00 | |
| 2–3 | 4 | 18.18 | 2 | 6.06 | 0 | 0 | |
| Previous chemotherapy | 0.036 | ||||||
| No | 9 | 40.91 | 25 | 73.53 | 13 | 50.00 | |
| Yes | 13 | 59.09 | 9 | 26.47 | 13 | 50.00 | |
| Previous surgery | < 0.001 | ||||||
| No | 20 | 90.91 | 33 | 97.06 | 15 | 57.69 | |
| Yes | 2 | 9.09 | 1 | 2.94 | 11 | 42.31 | |
3DCRT = three-dimensional conformal radiation therapy; BMI = body mass index; ECOG PS = Eastern Cooperative Oncology Group performance status; IMRT = intensity-modulated radiotherapy; PBT = proton-beam therapy; RBE = relative biological effectiveness; SD = standard deviation.
a
Chi-square test for categorical variables and analysis of variance for continuous variables.