(A) Double dissociation from [29], wherein patterns of the orbitofrontal cortex (OFC) response to visual stimuli were found to predict differences in subjective valence in novel subjects whereas ventral temporal cortex (VTC) activation predicted the items conveyed in the images. Brain regions highlighted in yellow depict regions of interest used for classification. (B) Peak classification weights from the Picture Induced Negative Emotion Signature [36], which maps whole-brain activation patterns to a continuous prediction of negative emotional experience. The model performed in excess of 90% accuracy when testing in independent subjects (A) reproduced, with permission, from [29]; (B) reproduced, with permission, from [36].