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. 2016 Mar 3;16(2):129–140. doi: 10.1007/s40268-016-0123-2

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Effects mediated by COX-1 and COX-2. COX cyclooxygenase, NSAIDs non-steroidal anti-inflammatory drugs, PGH2 prostaglandin-H2, PGI2 prostaglandin I2, TxA2 thromboxane A2, PGD2 prostaglandin D2, PGE2 prostaglandin E2, PGF2 prostaglandin F2α