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Type A phase solubility diagram of HPB/Prg 2:1 complex. The stoichiometry and complex formation constant of HPB/Prg complex were measured according to Higuchi and Connors [64], by phase solubility experiment. The resulting diagram is a type A curve with a 1:2 guest:host complex stoichiometry. HBP hydroxypropyl-β-cyclodextrin, Prg progesterone
