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. 2016 Apr 30;16(2):165–172. doi: 10.1007/s40268-016-0126-z

Table 3.

Change in objective function value for reduced models

Removing df dOFV
WT at V/F 0 14.36
WT at CL/F 0 12.61
WT at CL/F and V/F 0 8.91
cov (CL/F, V/F) 1 11.77
Progesterone effect 1 7.01
Inhibin B effect 1 78.01

The resulting dOFV when removing covariates or the correlation between CL/F and V/F [cov(CL/F,V/F)]

F bioavailability, CL/F apparent clearance, V/F apparent volume of distribution, WT body weight, df degrees of freedom, dOFV difference in objective function value