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. 2016 Mar 30;16(2):229–238. doi: 10.1007/s40268-016-0132-1

Table 6.

Ninety percent confidence intervals of ln-transformed pharmacokinetic parameters between the administration of levetiracetam 3DP fast melt under fed conditions vs. levetiracetam 3DP fast melt under fasting conditions in healthy volunteers

Parameter Ratio (fed/fast) 90 % confidence intervals
Lower Upper
lnC max 63.85 59.79 68.19
lnAUC0–T 94.45 92.58 96.36
lnAUC0–∞ 94.93 93.00 96.89

3DP three-dimensional printing, AUC 0–T area under the plasma concentration–time curve from time zero to the time of the last measurable concentration, AUC 0–∞ area under the plasma concentration–time curve from time zero to infinity, C max maximum observed plasma concentration, ln natural logarithm