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. 2015 Dec 22;37(6):7729–7739. doi: 10.1007/s13277-015-4597-2

Table 3.

Binding kinetics and affinities for the Tg antibodies E40, E44, E45, E47, I15, and I24

MAb SPR analysis Estimates from equilibrium analysis
K a
[M−1 s−1]
K d
[M−1 s−1]
K D
[M]
K D
[M]
E40 3.32 × 105 3.69 × 10−4 1.1 × 10−9 1.2 × 10−9
E44 3.14 × 105 1.29 × 10−4 4.1 × 10−10 3 × 10−10
E45 4.99 × 105 1.98 × 10−4 4.0 × 10−10 2 × 10−10
E47 2.95 × 105 3.23 × 10−5 1.1 × 10−10 6 × 10−10
I15 2.46 × 105 6.29 × 10−5 2.6 × 10−10 3 × 10−10
I24 4.24 × 105 2.15 × 10−4 5.1 × 10−10 2 × 10−10