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. 2016 May 8;2016:1348347. doi: 10.1155/2016/1348347

Table 2.

Principle characteristics of the studies included in the meta-analysis for association between eNOS rs1799983 and POAG.

First author Cohorts Year Ethnicity Genotyping Case Control Control
Size TT TC CC MAF Size TT TC CC MAF HWE (p)
Lin [15] All 2005 Asians Taqman 66 55 11 0 0.08 100 84 16 0 0.08 0.38

Fan [16] All 2010 Asians NA 397 310 77 10 0.12 201 157 40 4 0.12 0.45

Kang [17] All 2011 Caucasians Taqman 518 202 232 84 0.39 1501 580 673 248 0.39 0.03
Male 2011 Caucasians Taqman 153 65 66 22 0.36 457 166 215 76 0.40 0.65
Female 2011 Caucasians Taqman 365 137 166 62 0.40 1044 414 458 172 0.38 0.02

Magalhães da Silva [18] All 2012 Caucasians Taqman 89 42 39 8 0.31 123 74 38 11 0.24 0.07
Male 2012 Caucasians Taqman 28 16 10 2 0.25 61 35 22 4 0.25 0.83
Female 2012 Caucasians Taqman 61 26 28 7 0.34 62 39 20 3 0.21 0.83

Emam [19] All 2014 Caucasians PCR-RFLP 160 63 59 38 0.42 110 60 38 12 0.28 0.12
Male 2014 Caucasians PCR-RFLP 76 32 26 18 0.08 56 30 19 7 0.08 0.17
Female 2014 Caucasians PCR-RFLP 84 31 33 20 0.12 54 30 19 5 0.12 0.44

NA: data not available; MAF: Minor Allele Frequency; HWE: Hardy-Weinberg equilibrium; PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism.