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. 2016 May 8;2016:8043983. doi: 10.1155/2016/8043983

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Copyright © 2016 Romina Croci et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

In vitro cytotoxicity effect of ivermectin formulated in liposomes (closed circles) on Vero-118 cells. For comparison the same experiments were performed using empty liposomal formulations (open circles). The following liposomal formulations were tested: #PC9-Ch1 and #PC9-Ch1-ive1.0 (a), #PC9-Br1 and #PC9-Br1-ive1.0 (b), #PC9-Br0.5 and #PC9-Br0.5-ive1.0 (c), and #PC18-Br1 and #PC18-Br1-ive1.0 (d). The phosphatidylcholine concentration (top x-axis) is related to empty liposomes while the ivermectin concentration (bottom x-axis) is related to ivermectin liposomes. Details on the identification codes and liposomal compositions are included in Table 1. Data represent the average of 2 determinations.