Table 2.
Half maximal cytotoxic concentration (CC50) expressed in μM for ivermectin and ivermectin-loaded liposomal formulations.
| Identification code | Vero-F | Vero-118 | BHK | RAW | Huh-7 |
|---|---|---|---|---|---|
| Ivermectin | 23.6 | 5.7 | 1.5 | 0.8 | 10.0 |
| 2-cmc | n.d. | 117.3 | 237.7 | 37.6 | n.d. |
| #PC3-Ch1-ive0.1 | n.d. | n.d. | n.d. | n.d. | ~10.0∗ |
| #PC3-Cl1-ive0.1 | n.d. | n.d. | n.d. | n.d. | ~10.0 |
| #PC3-Br1-ive0.1 | n.d. | n.d. | n.d. | n.d. | >10.0∗ |
| #PC9-Ch1-ive1.0 | >25.0 | >25.0 | 8.4 | 2.2 | ~10.0∗ |
| #PC9-Br0.5-ive1.0 | >25.0 | >25.0 | 8.5 | 2.2 | n.d. |
| #PC9-Br1-ive1.0 | >25.0 | >25.0 | 4.3 | 2.2 | ~10.0∗ |
| #PC18-Br1-ive1.0 | >25.0 | >25.0 | >25.0 | >25.0 | n.d. |
n.d. = not determined; ∗after 48 h of cell culture incubation.