Table 4.
Results of propensity score matching of 2,308 patient-pairs undergoing either surgical resection or definitive CRT. Patients were matched for variables including: age, race, gender, income, type of treatment facility, comorbidity score, and tumor size. Continuous variables are displayed as mean +/− standard deviation. Categorical variables are displayed as number (% total).
| Patient Characteristics |
Definitive chemoradiation n= 2,308 |
Surgical resection n= 2,308 |
p-Value | |
|---|---|---|---|---|
| Age at diagnosis (years) | 68.9 +/− 9.0 | 68.9 +/− 8.9 | 0.81 | |
| Male Gender | 1,279 (55%) | 1,292 (56%) | 0.72 | |
| Caucasian | 2,030 (88%) | 2,024 (88%) | 0.82 | |
| Academic Center | 508 (22%) | 511 (22%) | 0.94 | |
| Annual Income > $35,000 | 1,450 (63%) | 1,415 (61%) | 0.30 | |
| Charlson/Deyo Score (CCI) | 0 | 1,317 (57%) | 1,304 (56%) | 0.91 |
| 1 | 710 (31%) | 715 (31%) | ||
| 2 | 281 (12%) | 289 (13%) | ||
| Tumor Size (mm) | 39.8 +/− 28.6 | 39.7 +/− 34.2 | 0.90 | |
| Radiotherapy | 2.308 (100%) | 397 (17%) | <0.001 | |
| Mean total radiation dose (cGy) | 6,619 +/− 3,409 | 5,293 +/− 1,580 | <0.001 | |
| Chemotherapy | None | 0 (0%) | 1,172 (51%) | <0.001 |
| Single Agent | 230 (10%) | 50 (2%) | ||
| Multi-agent | 1,862 (81%) | 954 (41%) | ||
| Chemo NOS | 216 (9%) | 132 (6%) | ||